on enemy death, on room clear, on damage taken etc. rocks, pots, stone blocks), All rocks spawn 0-2 blue spiders when destroyed, UNLOCK: Unlock this item by defeating Delirium as Tainted Keeper, When used, spawns a random shop item or consumable, however you have to pay the relevant cost to pick it up, Can include anything that would appear in the shop, UNLOCK: Unlock this item by defeating The Beast as Keeper, Item Pool: Shop, Secret Room, Wooden Chest, With every bar of charge this item has, a different consumable is shown inside the Jar. Doors remain open when entering a room with enemies in it. Film & Animation; Autos & Vehicles; Music; Pets & Animals; Sports; . Secret Rooms, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lazarus, Every time you take damage, you drop up to 2 different types of consumables on the ground, Dropped consumables can be any variant of its kind - e.g. the lost item pool, cat, bone, pink, grey, gray, guppys paw, guppy paw, Gives a 1/3 chance for room clear rewards to become a normal or locked chest, and a 1/3 chance to reward nothing at all, Doesn't affect coins dropped after waves in Greed Mode, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Throwing this at the Great Gideon boss will trigger a special animation and reveal a crawl space containing several chests and items! Lazarus - Every time Lazarus dies, gives +21.6 temporary Damage Up, gradually fading over 1 minute. ?s soul, blue baby's soul, blue babys soul, When you kill an enemy, you have a chance to get +0.5 damage up for the current room, UNLOCK: Unlock this item by beating the Dark Room with Samson, *, hair, pony, tail, brown, red, samsons lock, Gives a 25% chance to reveal map icons at the start of a new floor (The same effect as the Compass), UNLOCK: Unlock this item by beating the Chest with Cain, When you kill an enemy, you have a chance to spawn a transparent Dead Bird familiar, The Dead Bird familiar deals 2 damage per tick to enemies while in contact with them, UNLOCK: Unlock this item by beating the Isaac boss with Eve, *, grey, gray, black, striped, eves bird foot, REPENTANCE - No longer replaces chests that have already spawned, UNLOCK: Unlock this item by beating Ultra Pride, * northernlion, drop the left hand, paw, bloody, bleeding, grey, gray, While held, tinted rocks and rocks with a crawlspace below them will flash white every 10 seconds, *, grey, gray, silver, lump, metal, stone, Turns all troll bombs into bombs which you can pick up and use, Super Troll bombs turn into 1+1 free double bomb pickups, Gives your tears a random worm effect every few seconds, The possible tear effects include: Whip Worm, Ring Worm, Wiggle Worm, Flat Worm, Hook Worm, Pulse Worm, Tape Worm and Lazy Worm, While held, Tape Worm doubles your range stat and halves your tear height stat, Every time you get hit, you have a chance to activate the D6, D20, D8, D10 or D12 effect. binding of isaac: repentance unlock guide. knife, red, silver, Gives a 33% chance of converting red heart drops into soul hearts. Repentance adds more than 100 new enemies, 5,000 new room layouts, 130 new items and much more. If you have 1 or less heart containers, this pill becomes Health Up, Hematemesis - Empties all but one red heart container and spawns 1-4 red hearts on the floor. Bombs, keys, cards, runes and batteries have a 20% chance, Can lead to game-breaking combinations with the D20 due to the amount of consumables and batteries spawned by the item sacks, REPENTANCE - Added to the Secret Room pool. Holding the fire button charges a spin attack (Damage * 8 + 10). However if you take damage a second time you die like the Lost does, Same effect as touching a white fire, but only lasts one room, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lost, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lilith, Spawns up to 25 random coins on the floor, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Keeper, Locusts are variants of blue flies, except they have special effects based on the color, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Apollyon, Gives you The Forgotten as a temporary familiar, with 2 Bone hearts and his bone weapon. You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items. Then, you must get a special key, which is composed of two pieces. Find it . Gives Isaac a little portal familiar, that moves across the screen as you're firing, The portal will suck up any consumables and trinkets it travels over, causing it to become larger and deal more contact damage, When the portal sucks up 4 pickups, it turns into a portal that can be used to teleport to unexplored rooms around the floor. red, pink, broken, Better chance to win while gambling at the Shell Game and Fortune Telling Machine, Higher chance to get a random drop after clearing a room, REPENTANCE - Lucky Foot now guarantees positive pill effects, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, starting, pink, white, yellow, A target is placed on the floor which can be controlled. * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, The Rosary Bead changes this to a 75%/25% chance of an angel or devil room (respectively), When Isaac takes damage, there is a chance he will gain the Gamekid effect, turning him invincible and dealing contact damage to any enemies he touches, The chance to activate the invincibility effect is affected by your luck stat and at +38 Luck it will activate every time you get hit, * , the lost item pool, nes, game, grey, gray, Tears shrink and grow in size as they go across the room, Does not appear to affect your damage and only the hitbox size of tears, Tears now move in a wave fashion across the room, While held, tears move in a spiral pattern across the screen at high speed, Effectively increases your range due to the tear pattern, Tears become flat and disc shaped giving them a larger hitbox, While this trinket is held, all items in the Shop cost 0 coins, After buying any 0 cent item in the Shop, the trinket disappears, UNLOCK: Unlock this item by beating the Chest with Lazarus, *, grey, gray, dollar, bill, note, cash, money, Isaac no longer takes damage from walking over spikes and blood creep while this trinket is held, * , the lost item pool, brown, pink, lump, ball, spot, 33% chance to drop a coin for every rock that you destroy, REPENTANCE - Previously was 100%, now 33%, UNLOCK: Unlock this item by destroying 100 rocks, Mom's Leg will now appear every 20 seconds and stomp down randomly in the room dealing 300 damage to enemies. Plus this gambling machine is simple and quick, unlike the Slot Machines of old. And then you have the T. Lost mega satan unlock. The next room you enter he will automatically fire a massive red brimstone laser for 4 seconds, dealing huge damage, The rage resets back to zero, and the cycle continues every 5 rooms cleared, UNLOCK: Unlock this item by defeating The Beast as Tainted Azazel, When using a card, pill, or rune, you also use a copy of the last 3 cards/pills/runes you used after picking up Echo Chamber, UNLOCK: Unlock this item by defeating The Beast as Tainted Apollyon, Spawns an Old chest at the start of all future floors, Old Chests work the same as Golden Chests, requiring a key to open but contain different items, The Old chest can contain: 3 trinkets (42% chance), 1-3 soul hearts (43% chance), a random item from the Old Chest pool (10% chance) or an angel room item (5% chance), Spawns a second chest in the mirrored floor of Downpour II or Dross II, but only if you had this item before entering the floor, UNLOCK: Unlock this item by defeating The Beast as Tainted Forgotten, Each time you take damage, a red flame orbital will appear around Isaac for the remainder of the floor, up to a maximum of 6, The flames deal contact damage which scales with your tear damage, Upon reaching 6 flames, they will also start to fire tears along with Isaac, dealing a flat 3.2 damage per tear, When entering a new floor, all the flames disappear, UNLOCK: Unlock this item by defeating The Beast as Tainted Bethany, Using this item swaps you between the character you started as, and Esau, which has 3 black hearts, +2 base damage and the ability to fly, This character keeps its own separate health and items. Spawns coins as The Keeper, I can see forever - Opens secret room and super secret room entrances on the current floor, I found pills - Changes the appearance of Isaac's face for the current room (Cosmetic change only), Lemon Party - Spawns a large yellow pool on the floor around you, damaging enemies which walk in it, Paralysis - Prevents you from moving for a short while, Pheromones - Applies the charm effect to all enemies in the room for a short while, Puberty - Causes Isaac to grow hair for the rest of the run. spikes, creep). Based on the Steam Workshop mod created by electoon and Erfly, *, dark side of the moon, rainbow, red, yellow, green, white, triangle, pink floyd, thought, Replaces Isaac's tears with eyeballs that can bounce off of each other, Issac's tears are no longer limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle, Added as part of the Afterbirth+ Booster Pack #3. Deflected tears turn into homing tears and fire back at enemies, dealing 2 damage. Based loosely on the Steam Workshop mod created by Extreme Ninja Home Makeover with changes by Edmund McMillen, *, lepracy, leprasy, leprosy, pink, red, bloody, lump, Gives you a random Harbinger familiar that changes every 10 seconds, Each harbinger behaves differently, based on any of the original 5 horsemen bosses, REPENTANCE - The harbingers will also randomly spawn their relevant Locust variant. Order of unlocks - Binding of Isaac: Rebirth Wiki Community External Communities Wiki in: Modified in Afterbirth, Modified in Afterbirth+, Modified in Repentance Order of unlocks Edit Rebirth Categories Community content is available under CC BY-NC-SA unless otherwise noted. When you take damage and the cannon breaks, you take an additional 2 full hearts of damage and gain the Anemic effect for the room. Type: Passive. grey, gray, lamp, UNLOCK: Unlock this item by making a Super Bandage Girl, * boss room pool, boss room item, pink, plaster, sticker, item room, treasure room, item room pool, the lost item pool, When used Isaac transforms into pacman, which makes him invincible for 6 seconds and does 40 contact damage to enemies per chomp, Everytime you 'eat' 2 enemies, you regain 1/2 heart of red health, You can't shoot tears while the effect is active, UNLOCK: Unlock this item by visiting 10 arcades, * item room, treasure room, item room pool, gameboy, grey, gray, white, A bag that floats around following Isaac and drops a random coin every 2 rooms, UNLOCK: Unlock this item by beating Isaac with Cain, * secret room pool, item room, treasure room, item room pool, bag, purple, pouch, A familiar which follows Isaac and shoots lasers, similar to the Technology item, Robo-Baby's laser is spectral and piercing (It will pass through rocks and objects in the environment), Robo-Baby's lasers deal 3.5 damage per hit, * item room, treasure room, item room pool, robo baby, robot baby, white, grey, gray, silver, red, A familiar which follows Isaac and drops half a red heart every 3 rooms, UNLOCK: Unlock this item by beating the Caves 30 times and defeating C.H.A.D, * lil chad, little chad, item room, treasure room, item room pool, the lost item pool, red, smile, face, bug, Any pickups are possible from this item, including Bombs, hearts, keys, coins, pills, batteries, tarot cards, runes etc, Doesn't produce microbatteries, only regular sized ones and rarely golden/mega batteries, UNLOCK: Unlock this item by beating each of the Seven Sins once, Item Pool: Item Room, Library, Devil Room, * library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red 7 book, grey, gray, black, A blue cross that follows Isaac and drops a soul heart every 7-8 rooms, REPENTANCE - The Relic now generates soul hearts less frequently, UNLOCK: Unlock this item by beating the Isaac boss with Maggy, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, This can make it confusing while navigating the room, Dataminer will randomly increase or decrease one of your stats by a small amount when used, Gives you the Fruit Cake effect for the room when used, which will give a random tear effect with every tear fired, All visual and tear effects reset after leaving the room, * data miner, red, pickaxe, minecraft, pixel, When used, this item will randomly change you into another character and remove the last item you picked up, All stat changes of the new character are applied (e.g. It isn't 100% effective but the effect is very strong and will deflect most shots under a bullet hell situation. Damage scales with total heart containers. Every 6 coins Bumbo will evolve to a new form except for level 4 which takes 12 coins, Level 2: Bumbo gains a body and crawls around the room, sometimes dropping random pickups, Level 3: It now fires tears in the same direction Isaac does, Level 4: Bumbo no longer fires tears but instead will chase enemies slowly and deal contact damage. 'One Makes you Larger' pills, Magic Mushroom etc, *, mtg, card, magic, gathering, green, brown, giant growth, Spawns 3 random cards on the floor when used, When used, this card will slow down enemies, Isaac's tears by -1 Shot Speed, but speed up Isaac's movement speed by +0.50 for the rest of the current room, UNLOCK: Unlock this item by getting both the Broken Watch and the Stop Watch in your collection, When used, removes the price tag from all items in the current shop or devil deal, making everything free, The effect of the Credit Card only lasts for the current room, UNLOCK: Unlock this card by beating Challenge #10 (Cursed!). Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. Explosion damage has increased to 100 (from 60). Cathedral: 1 Angel Room Item + 1 Eternal Heart, Pandora's Box considers XL floors to always be the first floor of a chapter, Alternative floors drop the same stuff e.g. in The Chest as Apollyon, Upon entering a room with enemies, spawns a Black Locust that deals quadruple Isaac's damage, applied as two hits of double damage, UNLOCK: Unlock this trinket by defeating The Lamb as Apollyon, At the start of each new hostile room you spawn 2-5 white attack flies, which will target a nearby enemy and deal double your tear damage to it, UNLOCK: Unlock this trinket by defeating Boss Rush as Apollyon, When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room, UNLOCK: Unlock this trinket by defeating Greedier Mode with Azazel, Stem Cell heals Isaac's red heart containers to 50% each floor, If Isaac already has 50% health or more, it heals half of a heart instead, UNLOCK: Unlock this trinket by defeating Greedier Mode with Samson, Fully recharges your active item at the start of each boss fight, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Zaratus, Gives you the Holy Mantle shield effect at the start of every new floor, which protects you from the next hit of damage you take, Does not recharge until the start of the next floor, Stacks with the effects from Holy Mantle and Blanket, but it does not stack with Holy Card, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ep and Mills, Using your active item while holding this trinket will drop it back on a pedestal on the ground, Also after taking damage, you have a very small chance to drop one of your passive items, One-time use active items will be consumed and not dropped, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by MarkusLeben and iguesti, *, yellow, golden, box, block, square, cube, Holding this trinket will cause the Angel mini bosses to drop normal items instead of Key Pieces, Added as part of the Afterbirth+ Booster Pack #2, designed by Edmund McMillen, While held, the last door Isaac went through stays open, allowing him to leave the room even if enemies are in it, This trinket works on boss rooms (except Ultra Greed) and devil rooms containing Krampus, allowing you to exit out mid-fight, UNLOCK: Unlock this trinket by blowing up doors and secret room walls 50 times, *, door, stop, wedge, cheese, wood, brown, hodor, game of thrones, Wylis, After being picked up, a yellow laser chain now flows through Isaac's familiars, Added as part of the Afterbirth+ Booster Pack #4 and based on the Steam Workshop mod created by Strawrat and Aczom, While held, spawns +1 friendly blue fly every time you pick up a coin, Added as part of the Afterbirth+ Booster Pack #5. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. With Keeper's buff of an additional Coin Heart, unlocking this item isn't that difficult compared to what it would have been in AB+. However after the attack you end up near the boss, which puts you in danger of taking damage too, Scales in damage and area of effect with the player's size, UNLOCK: Unlock this item by defeating Delirium as Jacob & Esau, When used will do a swipe attack in any direction. Counts as 1 of 3 poop items needed towards the Oh Crap transformation. Unlockables can be viewed by going to the "Stats" section in the main menu, and then viewing "Secrets" in the left-center of the screen. treasure room, item room pool, white, Upon use, consumes a coin and deals damage to everything in the room, Damage dealt is equal to your tear damage * 2 + 10, REPENTANCE - Damage buffed, previously it was damage * 2. All your items and consumables are temporarily removed while in the abandoned mine, The room to access Knife Piece 2 only appears if you have Knife Piece 1 already, You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door, When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, This is a one time use item that teleports you to an alternate floor, which contains every single item in the game, The items are spread between several different rooms all on pedestals. blue, white, triangle, Isaac's tears become large, brown and will penetrate all objects and enemies (piercing + spectral), Despite the increase in tear size, Dead Onion does NOT increase your damage stat. Further Reading: The Binding of Isaac: Repentance Review; Version 1.78 brings with it a plethora of gameplay changes, which we know you're itching to check out. ?, Satan and The Lamb as Tainted Forgotten, Gives you +1 Bone Heart every time you enter a new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Forgotten, Dropping this trinket again removes the transformation if you dont have 3 other Guppy items, UNLOCK: Unlock this trinket by defeating Isaac, ?? ), UNLOCK: Unlock this trinket by defeating Mother as Tainted Isaac, Causes Item rooms and Shops to appear in the Cathedral, UNLOCK: Unlock this trinket by defeating Isaac, ?? Battery - 6.6% chance, Also adds a 20% chance to spawn a fly if the original drop was a coin, UNLOCK: Unlock this trinket by defeating Isaac, ?? Returning back through the mirror door returns you back to normal again. It also doesn't do poison damage despite having the tagline 'toxic aura tears', * item room, treasure room, item room pool, brown, pink, purple, plant, Upon entering every 4th unexplored room, the Broken Watch will either slow down or speed up all enemies in the room, The slow effect is much more common than the speed up, * shop room pool, shop item pool, blue, grey, gray, smashed, clock, broken stop watch, broken stopwatch, A blue boomerang which can be thrown in a similar fashion to Mom's Knife, to stun any enemies it hits and deal damage, The damage dealt by the Boomerang is equal to double your tear damage, The boomerang can also be used to grab pickups and consumables from a distance, similar to the legend of zelda boomerang, The range of the boomerang is affected by range, with number one the distance is very short and makes the item a lot less effective, The Boomerang can be used to kill shopkeeper corpses, allowing you to farm their drops for coins, items, Steam Sale etc, REPENTANCE - Boomerang is now piercing, and has far less downtime between throwing it and being able to fire tears again, * shop room pool, shop item pool, crescent, moon, blue, grey, gray, * boss room pool, boss room item, grey, gray, punk, Decreases the size of Isaac, and your player hitbox, making you less likely to be hit, * boss room pool, boss room item, pro plus, tablet, medicine, white, * boss room pool, boss room item, grey, orange, family, picture, * boss room pool, boss room item, mushroom, fungi, fungus, Item Pool: Boss Room, Gold/Stone Chest, Key Beggar, * boss room pool, boss room item, brass, bronze, brown, gold, REPENTANCE - Also drops the Match Stick trinket, * boss room pool, boss room item, white, red, * boss room pool, boss room item, syringe, needle, grey, purple, pink, * boss room pool, boss room item, the lost item pool, dog, biscuit, brown, orange, A one-time use item which when used, will duplicate any pedestal items or consumables in the current room, If used in a shop, the duplicated items can be taken for free, If used on a trinket, another random trinket will spawn instead of a duplicate, If used in the Boss Rush, all the duplicates can be taken for free as well as one of the original items, If used in a Devil Room or Black Market, the duplicates can be taken for free, When used, copies the effect of the pill you are currently holding without consuming it, The charge time of this item depends on the quality of the pill you're holding, When used, has a 50% chance to drop one random type of coin (penny, nickel or dime), UNLOCK: Unlock this item by donating 33 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this item after beating Isaac with Keeper, With this item, at the start of every room you will deal double your tear damage to the entire room in a poison effect, Enemies killed now also leave a pool of creep on the ground where they died. - When used, shoots an Ipecac explosive shot. the lost item pool, white, black, Each time you take damage, you gain a damage up which lasts for the rest of the floor and turn a darker red colour each time, After taking 6 hits Bloody Lust doesn't give you any further damage increases, Damage given for each hit increases as follows: +0.5, +0.7, +0.9, +1.1, +1.3, +1.5, REPENTANCE - The damage increments have changed slightly, UNLOCK: Unlock this item by beating the Isaac boss with Samson, * item room, treasure room, item room pool, the lost item pool, starting, red, blood, drop, Upon use, reveals the map and drops either a soul heart or a random card/rune (50% chance for each), It reveals the location of the secret room, however it doesn't reveal the Super secret room, Has a chance to drop from playing a fortune machine. With respect to how to find these rooms, the initial chance of a Planetarium appearing is jus with Lilith, After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops, Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim, It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each, After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected, UNLOCK: Unlock this item by beating Boss Rush with Lilith, Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear, A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts, While the effect is active, tears do double damage and have -0.30 Shot Speed, The crown will glow blue while active, if inactive it will appear grey, The effect will also deactivate for the rest of the current room when you take damage, regardless of your health, When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies, REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999, UNLOCK: Unlock this item by beating The Chest floor with Keeper, A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage, While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus), The aura deals 2.5 damage per tick or about 7.5 - 10 damage per second, UNLOCK: Unlock this item by beating The Lamb with Lilith, Gives you a different tear effect with every tear that you fire, Tear effects include: Anti-Gravity, Ball of Bandages (Lvl 4), Bumbo (Lvl 3), Continuum, Cupid's Arrow, Compound Fracture, Euthanasia, Explosivo, Eye of Greed, Fire Mind, Flat Stone, Flat Worm, God's Flesh, Godhead, Head of the Keeper, Holy Light, Hook Worm, Ipecac, Iron Bar, Jacob's Ladder, Knockout Drops, Lachryphagy, Little Horn, Lodestone, Mom's Contacts, Mom's Eyeshadow, Mom's Perfume, Mucormycosis, My Reflection, Mysterious Liquid, Ocular Rift, Ouija Board, Ouroboros Worm, The Parasite, Parasitoid, Polyphemus, Pop!, Proptosis, Pulse Worm, Ring Worm, Rotten Tomato, Rubber Cement, Serpent's Kiss, Sinus Infection, Spider Bite, Strange Attractor, Sulfuric Acid, Technology Zero, Tiny Planet, Trisagion and Wiggle Worm, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. yellow book how to, * boss room pool, boss room item, bone, red, brown, Gives Isaac a random tarot card when picked up, * boss room pool, boss room item, eight, grey, gray, Drops 4 random pills on the floor around Isaac, Item Pool: Shop, Boss Room, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, shop room pool, shop item pool, bag, pouch, moms coin purse, mom coin purse. Stat Down becomes Stat Up, 'Bad Trip' turns into 'Balls of Steel' and 'Amnesia' turns into 'I can see forever', * astrology, astronomy, item room, treasure room, item room pool, blue glow, m, Balances out your main stats to bring the high and low stats closer to an average value, All future stat upgrading items will now instead spread out across all other stats. There are lots of things to unlock, with many of them connected to defeating certain bosses. purple, pink, mask, face, Puts a shield in front of Isaac which blocks projectiles, The shield will rotate based on the direction in which Isaac is firing tears, * angel room pool, god room pool, angel room item, blue, silver, metal, Gives Isaac a laser that will fire at random intervals in addition to your normal tears, Each laser does damage equal to your current tear damage, The laser will occasionally fire with one of these effects: Hook Worm, Spoon Bender, Tiny Planet, Mysterious Liquid, Rubber Cement, Luck has no effect on the rate at which Tech.5 fires and does not scale with items that increase your tears stat, UNLOCK: Unlock this item by beating Challenge #18 (The Host), * technology.5, tech 5, item room, treasure room, item room pool, white, red, eye, robot, Isaac now shoots two tears at once, but dealing -20% damage each, Unlike the Inner Eye and Mutant Spider items, this double shot item does not give a tears down, * 20 20, 2020, item room, treasure room, item room pool, black glasses, spectacles, Reveals the locations of the secret and super secret room for the current floor and all future floors, UNLOCK: Unlock this item by donating 10 pennies to the Shop, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, 130 new items and much more room clear, on room clear, damage! 8 + 10 ) Music ; Pets & amp ; Vehicles ; Music ; Pets & amp ; Vehicles Music... 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